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LY 345899
CAS No. 10538-99-5
LY 345899 ( —— )
产品货号. M22500 CAS No. 10538-99-5
LY 345899 is a Folate analog and is a methylenetetrahydrofolate dehydrogenase and MTHFD2 inhibitor (IC50: 96 nM and 663 nM, respectively and a Ki: 18 nM for MTHFD1).
纯度: >98% (HPLC)
COA
Datasheet
HNMR
HPLC
MSDS
Handing Instructions
| 规格 | 价格/人民币 | 库存 | 数量 |
| 5MG | ￥3021 | 有现货 |
|
| 10MG | ￥4504 | 有现货 |
|
| 25MG | ￥7233 | 有现货 |
|
| 50MG | ￥9882 | 有现货 |
|
| 100MG | ￥13203 | 有现货 |
|
| 500MG | ￥26568 | 有现货 |
|
| 1G | 获取报价 | 有现货 |
|
生物学信息
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产品名称LY 345899
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注意事项本公司产品仅用于科研实验，不得用于人体或动物的临床与诊断
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产品简述LY 345899 is a Folate analog and is a methylenetetrahydrofolate dehydrogenase and MTHFD2 inhibitor (IC50: 96 nM and 663 nM, respectively and a Ki: 18 nM for MTHFD1).
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产品描述LY 345899 is a Folate analog and is a methylenetetrahydrofolate dehydrogenase and MTHFD2 inhibitor (IC50: 96 nM and 663 nM, respectively and a Ki: 18 nM for MTHFD1).
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同义词——
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通路Others
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靶点Other Targets
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受体MTHFD1
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研究领域——
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适应症——
化学信息
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CAS Number10538-99-5
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分子量471.42
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分子式C20H21N7O7
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纯度>98% (HPLC)
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溶解度DMSO:125 mg/mL (265.16 mM; Need ultrasonic)
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SMILESNc1nc(=O)c2N3C(CN(C3=O)c3ccc(cc3)C(=O)N[C@@H](CCC(O)=O)C(O)=O)CNc2[nH]1
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化学全称——
运输与储存
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储存条件(-20℃)
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运输条件With Ice Pack
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稳定性≥ 2 years
参考文献
1. Schmidt A, et al. Structures of three inhibitor complexes provide insight into the reaction mechanism of the human methylenetetrahydrofolate dehydrogenase/cyclohydrolase. Biochemistry. 2000 May 30;39(21):6325-35.
产品手册
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